CANCER THERAPY AND RISK OF CONGENITAL MALFORMATIONS IN CHILDREN FATHERED BY MEN TREATED FOR TESTICULAR GERM-CELL CANCER: A NATIONWIDE REGISTER STUDY.

Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study.

BackgroundBecause of the potential mutagenic effects of chemo- and radiotherapy, there is concern regarding increased risk of congenital malformations (CMs) among children of fathers with cancer.Previous register studies indicate increased CM risk among children conceived after paternal cancer but lack data on oncological treatment.Increased CM ris

read more

Is Early Conversion to mTOR Inhibitors Represent a Suitable Choice in Renal Transplant Recipients? A Systemic Review of Medium-term Outcomes

Background: Immunosuppressive therapies are important parts of renal transplantation.Objective: To assess the present literature on the effectiveness of early introduction of mTOR inhibitors with or without calcineurin inhibitors (CNI) in renal transplant recipients in terms of renal functioning and graft survival.Methods: The current literature wa

read more


The Phylogeny, Metabolic Potentials, and Environmental Adaptation of an Anaerobe, Abyssisolibacter sp. M8S5, Isolated from Cold Seep Sediments of the South China Sea

Bacillota are widely distributed in various environments, owing to their versatile metabolic capabilities and remarkable adaptation strategies.Recent studies reported that Bacillota species were highly enriched in cold seep sediments, but their metabolic capabilities, ecological functions, and adaption mechanisms in the cold seep habitats remained

read more